Skip to content
Peyote.comMedicine, mapped

The directory / Psilocybin

Psilocybin retreats in Oregon

21 psilocybin centres in Oregon, listed because psilocybin is licensed there. Every licensed centre on the state register is listed except those it shows as closed, withdrawn or surrendered. Nothing operating underground is listed.

Is psilocybin legal in Oregon?

Licensed · Psilocybin

State-licensed psilocybin services under ORS 475A (Measure 109), for adults 21 and over.

The Oregon Health Authority licenses psilocybin service centres, facilitators and manufacturers under ORS 475A. Psilocybin may be used only at a licensed service centre with a facilitator, with no take-home or retail sale, and only by adults 21 and over. Cities and counties can vote to ban psilocybin businesses locally. Psilocybin remains a Schedule I substance under federal law.

What the sources say

Source: Oregon Psilocybin Services (OPS) Licensee Directory, Oregon Health Authority, Public Health Division, Oregon Psilocybin Services Section, read 28 Sep 2026. The OHA directory lists only licensees who consent to be listed, publishes no licence numbers, cities or statuses, and OHA says it is not used for licence verification. Cities come from each centre's own website. Centres the register shows as closed, withdrawn or surrendered are not listed. A state licence is not an audit.

More jurisdictions and substances in the legal status table.

Law changes in Oregon

Dated changes to the law, regulation or official guidance, newest first, each with its source. Every country in the log.

  1. Ballot

    Local bans on psilocybin businesses passed in 16 of the 17 Oregon places that voted on them in the November 2024 election. (OPB, 7 Nov 2024)

  2. Regulation

    The Oregon Health Authority opened licence applications for psilocybin service centers, facilitators, manufacturers and laboratories under OAR chapter 333, division 333. Licensed service centers began opening to clients in summer 2023. (Oregon Health Authority, current page)

  3. Ballot

    Under ORS 475A.718 local opt-outs, 25 counties and 26 cities banned psilocybin businesses at the November 2022 election, as OPB reported. (Oregon Health Authority, current page; OPB, 7 Nov 2024)

  4. Ballot

    Voters approved Ballot Measure 109, codified as ORS 475A, directing the Oregon Health Authority to license and regulate psilocybin products and psilocybin services. (Oregon State Legislature, current edition)

What a licensed session involves

  1. PreparationA required session of roughly two hours with your licensed facilitator, often available over video. Intentions, history, expectations, and what will happen on the day.
  2. Administration6 to 8 hours at a licensed service centre, with a facilitator present the whole time. State rules set a minimum stay based on dose. You cannot take the product away.
  3. IntegrationThe facilitator follows up within 72 hours, with an integration session of about two hours offered.
  4. PracticalitiesPlan 3 to 5 days near the centre: a day or two before to prepare, and a day or two after before travelling. No prescription or diagnosis is required, and no medical referral.

The general shape of licensed services. These centres do not publish programme prices on the register, so none are shown; ask each centre for a written quote.

What to check before booking

Oregon's rules set some medical exclusions in law; these are the sourced ones, and the questions any licensed centre should ask you.

  • Lithium: seizure riskSerious risk

    An analysis of online reports found that 47% of 62 reports of lithium taken with a classic psychedelic (such as psilocybin or LSD) involved seizures and 39% involved medical attention, while none of 34 lamotrigine reports did. The authors provisionally concluded psychedelic use may pose a significant seizure risk for people on lithium. (Pharmacopsychiatry, 2021)

  • Oregon bars recent lithium usersSerious risk

    Oregon's required Client Information Form asks whether the client has taken lithium in the last 30 days; a yes answer means the client may not participate in an administration session. (Oregon Health Authority, Public Health Division, 2026)

  • Psychosis and severe psychiatric historySerious risk

    Published research safety guidelines recommend excluding volunteers with a personal or family history of psychotic disorders or other severe psychiatric disorders, and note prolonged psychoses triggered by hallucinogens are less common than acute distress. Oregon's Client Information Form bars anyone who has ever been diagnosed with or treated for active psychosis. (Journal of Psychopharmacology, 2008; Oregon Health Authority, Public Health Division, 2026)

  • Bipolar disorderSerious risk

    In an international survey of 541 people with self-reported bipolar disorder who had used psilocybin, 32.2% described new or increasing symptoms after trips, prominently manic symptoms, sleep problems and anxiety; 3.3% used emergency medical services. The authors say bipolar symptoms may emerge or intensify after psilocybin use. (Journal of Psychopharmacology, 2023)

  • Tricyclic antidepressants and lithium may intensify effectsWorth knowing

    A small retrospective questionnaire study (10 people using LSD, not psilocybin) found chronic tricyclic antidepressant or lithium use was associated with subjectively stronger physical, hallucinatory and psychological responses, while chronic MAOI use was associated with weaker responses. (Behavioural Brain Research, 1996)

  • Blood pressure and heart rateWorth knowing

    NIDA states that psilocybin typically raises blood pressure and heart rate, which may be dangerous for people with heart conditions. A 2024 meta-analysis of psychedelic trials found an increased risk of elevated heart rate and systolic and diastolic blood pressure at all dose ranges during the acute phase. (National Institute on Drug Abuse (NIH); Psychiatry Research, 2024; EMCDDA (now EUDA), via Internet Archive snapshot 2024-06-18)

  • Oregon's mandatory client screening questionsWorth knowing

    Before any Oregon administration session, the client must complete a Client Information Form with a facilitator, answering yes/no questions on lithium use, current treatment for medical or mental health conditions, mushroom allergy, medications, thoughts or history of harming self or others, active psychosis and pregnancy or breastfeeding. Current thoughts of harming self or others, lithium in the last 30 days, or a history of active psychosis rule out a session; clients who are pregnant or breastfeeding must be told the risks are unknown. (Oregon Health Authority, Public Health Division, 2026)

Every cited psilocybin safety fact

Questions, answered from the data

Is psilocybin legal in Oregon?
Oregon licenses psilocybin service centers, facilitators and manufacturers under ORS 475A, regulated by the Oregon Health Authority, for adults 21 and over, while psilocybin stays Schedule I under federal law. Sources: Oregon Health Authority, current page; Oregon State Legislature, current edition; Legal Information Institute (Cornell) reproducing the U.S. Code, current text.
How many psilocybin retreats are there in Oregon?
Peyote.com lists 21 licensed psilocybin centres in Oregon, from the Oregon Psilocybin Services (OPS) Licensee Directory (Oregon Health Authority, Public Health Division, Oregon Psilocybin Services Section), read 28 Sep 2026. Centres the register shows as closed, withdrawn or surrendered are not listed. A listing is not an endorsement or a safety rating.
When did the law on psilocybin in Oregon last change?
The most recent change in our log is dated Nov 2024. Local bans on psilocybin businesses passed in 16 of the 17 Oregon places that voted on them in the November 2024 election. (Source: OPB, 7 Nov 2024.) The one before it is dated 2 Jan 2023. The Oregon Health Authority opened licence applications for psilocybin service centers, facilitators, manufacturers and laboratories under OAR chapter 333, division 333. Licensed service centers began opening to clients in summer 2023. (Source: Oregon Health Authority, current page.)

Before you go

  • Fireside Project, a free, confidential psychedelic peer support line for people during and after an experience. Worth saving before a session, not after.

Questions this data answers

Other locations

The dispatch

Laws change. Centres change. Know before you book.

A brief, sent only in weeks when something changes: jurisdictions that shifted, listings added or revised, and the research worth reading. No hype, no sourcing talk.

Educational only. Not medical advice. Unsubscribe any time.