Clinical trials / Tennessee
Psychedelic and ketamine trials recruiting in Tennessee
4 trials registered on ClinicalTrials.gov were recruiting at one or more sites in Tennessee on 26 Oct 2026. By substance: Ketamine / esketamine 4. By condition: depression 2, opioid use disorder 1, cancer and end-of-life distress 1.
From the ClinicalTrials.gov registry (US National Library of Medicine), read through its public API on 26 Oct 2026: studies marked as recruiting whose interventions name the substance. Titles, sponsors, phases, conditions and sites are the registry's own entries, written by the sponsors. We have not vetted any trial, and recruiting status changes; the registry record and the study team have the current eligibility rules.
Phase 3Ketamine / esketamineNCT06713616
PCORI Comparative Effectiveness Study-Esketamine (Spravato) vs. Ketamine-Equivalence Study
- Conditions:
- Depression
- Sponsor:
- Yale University
- Who:
- ages 18 Years and over, 400 participants planned
- Athena Care, Nashville, Tennessee
ObservationalKetamine / esketamineNCT06725277
The OBSERVE Protocol
- Conditions:
- Major Depression Disorder
- Sponsor:
- Yale University
- Who:
- 450 participants planned
- Athena Care, Nashville, Tennessee
Phase 1/2Ketamine / esketamineNCT05156060
Gabapentin & Ketamine for Prevention/Treatment of Acute/Chronic Pain in Locally Advanced Head and Neck Cancer
- Conditions:
- Head and Neck Cancer; Locally Advanced Head and Neck Carcinoma
- Sponsor:
- Natalie Lockney
- Who:
- ages 21 Years and over, 64 participants planned
- Vanderbilt-Ingram Cancer Center, Nashville, Tennessee
Phase 4Ketamine / esketamineNCT06506565
Low-Dose Ketamine Infusion During Burn Wound Care (IMPROVE)
- Conditions:
- Burn; Pain; Dissociation; Opioid
- Sponsor:
- University of Tennessee
- Who:
- ages 18 Years and over, 140 participants planned
- Regional One Health, Memphis, Tennessee