Clinical trials / Alabama
Psychedelic and ketamine trials recruiting in Alabama
4 trials registered on ClinicalTrials.gov were recruiting at one or more sites in Alabama on 26 Oct 2026. By substance: Psilocybin 3, Ketamine / esketamine 1. By condition: depression 2.
From the ClinicalTrials.gov registry (US National Library of Medicine), read through its public API on 26 Oct 2026: studies marked as recruiting whose interventions name the substance. Titles, sponsors, phases, conditions and sites are the registry's own entries, written by the sponsors. We have not vetted any trial, and recruiting status changes; the registry record and the study team have the current eligibility rules.
Phase 3Ketamine / esketamineNCT07227454
A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder (AVENUE)
- Conditions:
- Depressive Disorder, Major
- Sponsor:
- Janssen Research & Development, LLC
- Who:
- ages 12 Years to 17 Years, 258 participants planned
- Also in:
- Brazil, Hungary, Italy, Romania, Spain, Taiwan
- University of Alabama at Birmingham, Birmingham, Alabama
Phase 3PsilocybinNCT07226232
Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression (PIVOT)
- Conditions:
- Major Depression
- Sponsor:
- VA Office of Research and Development
- Who:
- ages 18 Years to 75 Years, 240 participants planned
- Birmingham VA Medical Center, Birmingham, AL, Birmingham, Alabama
- Tuscaloosa VA Medical Center, Tuscaloosa, AL, Tuscaloosa, Alabama
Early phase 1PsilocybinNCT05068791
Psilocybin-facilitated Treatment for Chronic Pain
- Conditions:
- Fibromyalgia, Primary
- Sponsor:
- University of Alabama at Birmingham
- Who:
- ages 25 Years to 65 Years, 30 participants planned
- UAB Beacon Tower, Birmingham, Alabama
Phase 2PsilocybinNCT05452772
5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder
- Conditions:
- Tobacco Use Disorder
- Sponsor:
- Johns Hopkins University
- Who:
- ages 21 Years and over, 66 participants planned, accepts healthy volunteers
- University of Alabama at Birmingham, Birmingham, Alabama