Integration Practices: Making Sense of Psychedelic Experiences
What integration means in clinical trials and Oregon law, what the evidence does and does not show, common practices, warning signs and how to choose an integration therapist.
What integration means
Integration is the work after a psychedelic session: making sense of what happened and deciding what, if anything, to change. A 2022 concept analysis found many competing definitions, covering a range of practices, and noted that integration is offered by therapists, coaches and other practitioners or done alone. (Frontiers in Psychology, 2022) That breadth is part of the problem. The word can describe a structured therapy session or a casual chat.
This article covers integration as a stage of formal treatment and as something people do after any lawful session. For what the trials show about each medicine, the condition pages are the place: psilocybin for depression and MDMA for PTSD. For handling a difficult session as it happens, see challenging experiences.
Integration in clinical trials and licensed programmes
Psychedelic trials wrap the drug in therapy before and after. In the first phase 3 MDMA trial for severe PTSD, 90 participants received MDMA or placebo in manualised therapy sessions, combined with three preparatory and nine integrative therapy sessions. (Nature Medicine, 2021) In a randomised psilocybin trial for major depression, two psilocybin sessions came with about 11 hours of supportive psychotherapy. (JAMA Psychiatry, 2021) The large single-dose psilocybin trials describe the support around the dose as psychological support. (New England Journal of Medicine, 2022; JAMA, 2023)
Oregon writes integration into law but makes it optional for the client. The facilitator who supervised an administration session must offer an integration session afterwards, and the client may decline it. (Oregon State Legislature, current edition) The legal psilocybin guide lists Oregon's licensed centres.
What the evidence does and does not show
The trials show results for a medicine given with therapy. They do not show what the integration part contributes. In the second phase 3 MDMA trial, both groups received the same therapy, so the difference between them measures MDMA plus therapy, not therapy alone. (Nature Medicine, 2023) None of the trials described here compared integration with no integration after the same dose.
A 2024 paper by integration researchers put it plainly: several integration models are theory-driven or have a history of clinical use, but "each lack any empirical support and thus cannot be described as evidence based". (Experimental and Clinical Psychopharmacology, 2024) They called for studies to develop and test integration methods. (Experimental and Clinical Psychopharmacology, 2024) Part of the difficulty is measurement: before a trial can test integration it needs a way to score it. In 2022 researchers published two questionnaires for this, one for engagement in integration activities and one for the inner sense of feeling integrated, with initial validation data. (Frontiers in Psychology, 2022) Tools like these are a starting point, not a result.
So claims that integration makes benefits last longer, or that people who skip it lose the benefit, go beyond the evidence. Integration is a reasonable part of care, and the trials that produced the best-known results included it, but its separate effect has not been measured.
Common practices, described honestly
The practices below are what people use. None is a proven treatment for anything that follows a psychedelic session.
Journalling. Writing down what happened soon after a session keeps details that fade. Reading and journalling were among the most common individual coping strategies in a study of 608 people who had difficulties lasting at least a day after a psychedelic experience. (Frontiers in Psychology, 2024)
Meditation and prayer. In the same study these were the most common individual strategies people described as helpful. (Frontiers in Psychology, 2024) Some people use yoga, walking or other body-based practices in the same way; there is no specific research on them after psychedelic experiences.
Talking it through. The most common social strategy was support from friends or family, followed by help from a therapist or coach. What people found helpful was feeling heard and accepted and not judged. (Frontiers in Psychology, 2024)
Peer integration groups. In a survey of 65 people who attended psychedelic integration groups, participants described community support and help processing their experiences, but also problems with group dynamics and with facilitators who were not adequately trained. (Psychedelic Medicine, 2025) An ethics paper suggests people may seek out these groups because of the disconnection and loneliness some feel afterwards, and that groups can offer community and shared coping strategies while carrying risks of their own. (International Review of Psychiatry, 2024)
Therapy. A licensed therapist can help with what a session stirred up, whether or not they specialise in psychedelics. A harm-reduction paper argues that therapists can meet clients before and after their own psychedelic experiences while staying within legal and ethical limits. (Harm Reduction Journal, 2021)
The first days and weeks
There is no tested schedule, so treat the following as sensible habits rather than a protocol.
The first two days. Rest, eat properly and avoid big decisions. Write notes before details fade, without trying to interpret them yet. If you took part in a programme, use the follow-up call or session it offers.
The first fortnight. Return to your notes and look for the two or three points that still seem important. Talk them over with one person you trust. Notice sleep, mood and energy, and compare them with how you were before.
After a month. Ask what, concretely, you want to do differently, and whether it is still a good idea away from the intensity of the session. Insights that feel certain during a session can look different later, and a change to a relationship, a job or a medicine deserves the same care as any other big decision. Any change to a prescribed medicine is a conversation with your prescriber.
Warning signs that need professional help
Most difficult feelings settle within days. Some do not. In a study of 608 people who reported extended difficulties after psychedelic use, the most common were anxiety and fear, existential struggle, social disconnection, depersonalisation and derealisation. For about a third the problems lasted more than a year, and for a sixth more than three years. Taking the drug in a guided setting was linked to a narrower range of difficulties. (PLOS ONE, 2023)
In a survey of 1,993 people describing their worst psilocybin experience, 7.6% of those whose experience was over a year earlier had sought treatment for lasting psychological symptoms. (Journal of Psychopharmacology, 2016) In a survey of 541 people with bipolar disorder who had used psilocybin, 32.2% described new or worse symptoms afterwards, prominently manic symptoms, sleep problems and anxiety. (Journal of Psychopharmacology, 2023)
See a doctor or a licensed mental health professional, rather than an integration group or coach, if you notice:
- Not sleeping for several nights, racing thoughts or unusual energy.
- Hearing or seeing things others do not, or beliefs that friends find alarming.
- Feeling unreal or detached from your body for more than a few days.
- Panic, low mood or anxiety that is getting worse, not better, after two weeks.
- Any thoughts of harming yourself or someone else.
In the US you can call or text 988 at any hour for free, confidential support. (Substance Abuse and Mental Health Services Administration (SAMHSA), current page) In an emergency call 911, or 112 in the EU and UK. The safety page has more.
How to choose an integration therapist
"Integration therapist" describes a service, not a licence. Integration is offered by therapists, coaches and other practitioners. (Frontiers in Psychology, 2022) Even Oregon's licensed psilocybin facilitators need a high school diploma, approved training and an exam, and the state may not require them to hold a degree. (Oregon State Legislature, current edition) A facilitator is not a clinician unless they also hold a clinical licence; Oregon law lets a licensed health or behavioural health professional who also holds a facilitator licence conduct preparation and integration sessions alongside their clinical work. (Oregon State Legislature, current edition)
Before booking, ask:
- What is your professional licence, in which state or country, and what is the licence number? Check it on the licensing board's public lookup.
- What training do you have in psychedelic experiences specifically?
- What do you do if you think I need a psychiatrist or a medical assessment?
- Do you sell or recommend retreats, ceremonies or substances? A therapist with a financial stake in your next session has a conflict.
- What do you charge per session, and can I claim it on my health insurance?
Peer groups suit some people, but in the integration group study participants raised concerns about whether facilitators were adequately trained. (Psychedelic Medicine, 2025) Ask who runs the group and what they do if someone is in crisis.
On cost, there is little published data. Oregon does not require licensed centres to report what psilocybin sessions cost, and integration sessions are no different. (Oregon Health Authority, 2026) Get the price in writing before the first session. If you are still planning a session, the preparation guide covers what to arrange beforehand.
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Related
- MDMA Therapy for PTSD: History, Trials and the FDA Decision
- Psychedelic-Assisted Therapy: A Comprehensive Overview
- Ketamine Therapy for Depression: What You Need to Know
Questions and answers
- What is psychedelic integration?
- Integration is the process after a psychedelic session of making sense of the experience and deciding what to change. A 2022 concept analysis found many definitions, covering a range of practices, offered by therapists, coaches and other practitioners or done alone. In clinical trials it means scheduled therapy sessions after each dosing session.Sources: Frontiers in Psychology, 2022; Nature Medicine, 2021
- Is psychedelic integration therapy evidence-based?
- Not on its own. Trials have tested medicines given with preparation and integration therapy, but not integration separately, and a 2024 review said existing integration models lack empirical support and cannot be called evidence based. Integration is a reasonable part of care, but its separate effect has not been measured.Sources: Experimental and Clinical Psychopharmacology, 2024; Nature Medicine, 2023The evidence, condition by condition
- When should I see a professional after a psychedelic experience?
- See a doctor or licensed mental health professional, rather than a peer group or coach, if you stop sleeping, have racing thoughts, see or hear things others do not, feel unreal for days, or get steadily worse. In a study of 608 people with extended difficulties after psychedelics, about a third had problems lasting more than a year. In the US, call or text 988 at any hour.Sources: PLOS ONE, 2023; Substance Abuse and Mental Health Services Administration (SAMHSA), current pageSafety and harm reduction
- Is an integration session required after legal psilocybin in Oregon?
- No. Oregon law requires the facilitator who supervised the administration session to offer an integration session afterwards, but the client may choose not to take part. The preparation session before dosing, by contrast, is mandatory for every client. An integration session may be held at the service centre or elsewhere, and the facilitator certifies that it took place.Source: Oregon State Legislature, current editionLegal psilocybin in the US
Sources
- MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study. Nature Medicine, 2021
- MDMA-assisted therapy for moderate to severe PTSD: a randomized, placebo-controlled phase 3 trial. Nature Medicine, 2023
- Call for evidence-based psychedelic integration (Gren J, Gorman I, Ruban A, Tyls F, Bhatt S, Aixala M). Experimental and Clinical Psychopharmacology, 2024
- Coming back together: a qualitative survey study of coping and support strategies used by people to cope with extended difficulties after the use of psychedelic drugs (Robinson OC et al.). Frontiers in Psychology, 2024
- Extended difficulties following the use of psychedelic drugs: A mixed methods study (Evans J et al.). PLOS ONE, 2023
- Psychedelic integration: An analysis of the concept and its practice (Bathje GJ, Majeski E, Kudowor M). Frontiers in Psychology, 2022
- Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder: A Randomized Clinical Trial. JAMA Psychiatry, 2021
- Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression. New England Journal of Medicine, 2022
- Single-Dose Psilocybin Treatment for Major Depressive Disorder: A Randomized Clinical Trial. JAMA, 2023
- ORS Chapter 475A - Psilocybin (ORS 475A.325, 475A.338, 475A.345, 475A.360). Oregon State Legislature, current edition
- The Psychedelic Integration Scales: Tools for Measuring Psychedelic Integration Behaviors and Experiences (Frymann T, Whitney S, Yaden DB, Lipson J). Frontiers in Psychology, 2022
- Participants' Experience of Psychedelic Integration Groups and Processes: A Qualitative Thematic Analysis (Modlin NL et al.). Psychedelic Medicine, 2025
- Psychedelic group-based integration: ethical assessment and initial recommendations (Cheung K, Propes C, Jacobs E, Earp BD, Yaden DB). International Review of Psychiatry, 2024
- Ethical and legal issues in psychedelic harm reduction and integration therapy (Pilecki B, Luoma JB, Bathje GJ, Rhea J, Narloch VF). Harm Reduction Journal, 2021
- Survey study of challenging experiences after ingesting psilocybin mushrooms: Acute and enduring positive and negative consequences. Journal of Psychopharmacology, 2016
- Risks and benefits of psilocybin use in people with bipolar disorder: An international web-based survey on experiences of 'magic mushroom' consumption. Journal of Psychopharmacology, 2023
- 988 Suicide & Crisis Lifeline. Substance Abuse and Mental Health Services Administration (SAMHSA), current page
- Oregon Psilocybin Services 2025 Year-End Data Summary Document. Oregon Health Authority, 2026