Psilocybin law in every state
Psilocybin law · MS
Is psilocybin legal in Mississippi?
ProhibitedSchedule I federally
Psilocybin is illegal in Mississippi: it is a Schedule I controlled substance under Miss. Code §41-29-113, and the state's 2026 psychedelic law funds ibogaine trials, not psilocybin.
Psilocybin is a controlled substance under state law with no programme for its use. Last checked 26 Oct 2026. Pending bills are re-checked weekly against the legislature; last change recorded 26 Oct 2026. Not legal advice.
Current status
- Psilocybin and psilocyn are listed in Schedule I, hallucinogenic substances, Miss. Code §41-29-113(d)(29) and (30), as reenacted by SB 2117 (2026) (Mississippi Legislature, 13 Mar 2026)
- HB 314, the Ibogaine Drug Development Clinical Trial Act, was approved by the Governor on 26 March 2026; it authorizes the State Department of Health to select a consortium to run an ibogaine clinical trial aimed at FDA approval. (Mississippi Legislature, 26 Mar 2026)
- SB 2056, approved 13 March 2026, provides for automatic state scheduling of an FDA-approved crystalline polymorph psilocybin drug once the DEA schedules it; it does not legalize psilocybin mushrooms. (Mississippi Legislature, 13 Mar 2026)
Decriminalized cities and counties
None found as of 26 Oct 2026.
A local lowest-priority measure tells city or county police and prosecutors where to spend their time. It does not change state or federal law, and state or federal officers can still enforce it.
Bills
| Bill | What it would do | Status |
|---|---|---|
| HB 3142026 | Ibogaine Drug Development Clinical Trial ActAuthorizes the State Department of Health to select a consortium to conduct an ibogaine drug development clinical trial and seek FDA approval. | Signed 26 March 2026 (Mississippi Legislature, 26 Mar 2026) |
| SB 20562026 | Automatic scheduling of FDA-approved crystalline polymorph psilocybinAutomatically places an FDA-approved, DEA-scheduled crystalline polymorph psilocybin drug on the state schedules. | Signed 13 March 2026 (Mississippi Legislature, 13 Mar 2026) |
| HB 5632026 | Controlled substances; provide for automatic scheduling of psilocybin after federal schedulingHouse version of automatic state scheduling of psilocybin after federal rescheduling. | Passed House; died on Senate calendar (Mississippi Legislature, 11 Mar 2026) |
Penalties
- Possessing less than 0.1 gram or two dosage units of a Schedule I substance other than marijuana is a misdemeanor punishable by up to 1 year and a fine up to $1,000 (Miss. Code §41-29-139(c)(1)(A)). (Mississippi Legislature, 2025)
- Possessing 0.1 gram up to 2 grams (or 2 to 10 dosage units) carries up to 3 years and a fine up to $50,000 (Miss. Code §41-29-139(c)(1)(B)). (Mississippi Legislature, 2025)
Federal law applies in Mississippi too
- Peyote and mescaline are listed in Schedule I(c) of the Controlled Substances Act, as are psilocybin, psilocyn, DMT and ibogaine. (Legal Information Institute (Cornell) reproducing the U.S. Code, current)
- Outside the exemptions, distributing a Schedule I substance not named in the large-quantity tiers carries up to 20 years and a fine of up to $1,000,000 for an individual on a first offence (21 U.S.C. 841(b)(1)(C)); simple possession carries up to 1 year and a minimum fine of $1,000 on a first offence (21 U.S.C. 844(a)). (Legal Information Institute (Cornell) reproducing the U.S. Code, current; Legal Information Institute (Cornell) reproducing the U.S. Code, current)
Questions and answers
- Is psilocybin legal in Mississippi?
- Psilocybin is illegal in Mississippi: it is a Schedule I controlled substance under Miss. Code §41-29-113, and the state's 2026 psychedelic law funds ibogaine trials, not psilocybin.
- Has any city in Mississippi decriminalized psilocybin?
- We found no city or county measure in Mississippi that makes psilocybin a low enforcement priority, as of 26 Oct 2026.
- Are there psilocybin bills in Mississippi?
- None is pending. Recent bills: HB 314, Signed 26 March 2026; SB 2056, Signed 13 March 2026; HB 563, Passed House; died on Senate calendar.
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