Dissociative
2-(2-chlorophenyl)-2-(methylamino)cyclohexanone
No traditional use - modern pharmaceutical.
At a glance
Reported effects
Legal status
Prescription medication, but also controlled substance for non-medical use.
Research
FDA approved for treatment-resistant depression. Ongoing research for various mental health conditions.
Zarate CA, et al. · Archives of General Psychiatry · 2006
Crossover trial in 18 people with treatment-resistant depression: one ketamine infusion lifted mood within hours, but effects faded for most within a week.
What the study foundBerman RM, et al. · Biological Psychiatry · 2000
First placebo-controlled trial of ketamine for depression: in 7 patients, one infusion cut depression scores within 72 hours.
What the study foundThe dispatch
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